Heterogeneity ofp53Mutational Status in Esophageal Squamous Cell Carcinoma
โ Scribed by Kuwabara, Shirou ;Ajioka, Yoichi ;Watanabe, Hidenobu ;Hitomi, Jiro ;Nishikura, Ken ;Hatakeyama, Katsuyoshi
- Book ID
- 108581597
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1998
- Tongue
- English
- Weight
- 429 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0910-5050
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## Abstract ## BACKGROUND Esophageal carcinoma is a particularly interesting tumor because of the dramatic difference in its incidence and geographic distribution among populations of similar ethnic origin. Epidemiologic data have suggested that many environmental exposures may be associated with
## Esophageal cancer (EC) in the Indian population presents in advanced stages with poor prognosis and warrants the identification of a non-invasive marker for early detection and better prognostic assessment. We have previously reported high prevalence of p53 protein accumulation in esophageal squ