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Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases

โœ Scribed by Doyon, Yannick; McCammon, Jasmine M; Miller, Jeffrey C; Faraji, Farhoud; Ngo, Catherine; Katibah, George E; Amora, Rainier; Hocking, Toby D; Zhang, Lei; Rebar, Edward J

Book ID
109911035
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
331 KB
Volume
26
Category
Article
ISSN
1087-0156

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Gene targeting using zinc finger nucleas
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Gene targeting using zinc finger nucleas
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โœ Porteus, Matthew H; Carroll, Dana ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 239 KB

The ability to achieve site-specific manipulation of the mammalian genome has widespread implications for basic and applied research. Gene targeting is a process in which a DNA molecule introduced into a cell replaces the corresponding chromosomal segment by homologous recombination, and thus presen