𝔖 Bobbio Scriptorium
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HEREDITARY RESISTANCE TO COUMARIN ANTICOAGULANT DRUGS IN MAN AND RAT

✍ Scribed by Robert A. O'Reilly; Judith G. Pool; Paul M. Aggeler†

Book ID
114878454
Publisher
John Wiley and Sons
Year
1968
Tongue
English
Weight
970 KB
Volume
151
Category
Article
ISSN
0890-6564

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The anticoagulant warfarin exemplifies a type of drug that exhibits high affinity to pharmacologic target sites of limited capacity, resulting in unusual concentration-dependent distribution and elimination properties. The time course of warfarin concentrations in the serum, liver, kidneys, muscle,