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Hereditary protein S deficiency from a novel large deletion mutation of the PROS1 gene detected by multiplex ligation-dependent probe amplification (MLPA)

โœ Scribed by Jong-Ha Yoo; Hee-Jin Kim; Ho-Young Maeng; Young-Ah Kim; Young-Kyu Sun; Jae-Woo Song; Jong-Rak Choi; Sun-Hee Kim; Kyung-A Lee


Book ID
116914047
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
377 KB
Volume
123
Category
Article
ISSN
0049-3848

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ATM gene alterations have been described in various lymphoproliferative malignancies suggesting that ATM contributes to lymphomagenesis. Using multiplex ligation-dependant probe amplification (MLPA), we screened 61 childhood lymphoid malignancies for ATM genomic deletion/duplication. Five samples we