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Inherited protein S deficiency as a reszult of a large duplication mutation of the PROS1 gene detected by multiplex ligation-dependent probe amplification

โœ Scribed by H.-S. CHOUNG; H.-J. KIM; G.-Y. GWAK; S.-H. KIM; D.-K. KIM


Book ID
109152584
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
252 KB
Volume
6
Category
Article
ISSN
1538-7933

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ATM gene alterations have been described in various lymphoproliferative malignancies suggesting that ATM contributes to lymphomagenesis. Using multiplex ligation-dependant probe amplification (MLPA), we screened 61 childhood lymphoid malignancies for ATM genomic deletion/duplication. Five samples we