𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hereditary nonpolyposis colorectal cancer: pitfalls in deletion screening in MSH2 and MLH1 genes

✍ Scribed by Wehner, Maria; Mangold, Elisabeth; Sengteller, Marlies; Friedrichs, Nicolaus; Aretz, Stefan; Friedl, Waltraut; Propping, Peter; Lifton, R

Book ID
110026325
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
134 KB
Volume
13
Category
Article
ISSN
1018-4813

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Hereditary nonpolyposis colorectal cance
Hereditary nonpolyposis colorectal cancer: Frequent occurrence of large genomic deletions in MSH2 and MLH1 genes
✍ Yaping Wang; Waltraut Friedl; Christof Lamberti; Matthias Jungck; Micaela Mathia πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 190 KB πŸ‘ 2 views

## Abstract Hereditary nonpolyposis colorectal cancer (HNPCC) is often caused by a deficiency in DNA mismatch repair. By using conventional methods of mutation analysis, point mutations in the DNA mismatch repair genes __MSH2__ and __MLH1__ have been detected in up to 64% of patients suspected of H

Characterization of MSH2 and MLH1 mutati
Characterization of MSH2 and MLH1 mutations in Italian families with hereditary nonpolyposis colorectal cancer
✍ Alessandra Viel; Maurizio Genuardi; Eugenia Capozzi; Francesca Leonardi; Alfonso πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 331 KB πŸ‘ 2 views

Mismatch repair genes MSH2 and MLH1 are considered to be the two major genes that are responsible for hereditary nonpolyposis colorectal cancer (HNPCC). Germline heterozygous inactivating mutations of MSH2 and MLH1 have been identified previously in a substantial fraction of individuals who are pred