Selective hepatobiliary transport defect
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Peter L. M. Jansen; Geny M. M. Groothuis; Wilbert H. M. Peters; Dirk F. M. Meije
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Article
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1987
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John Wiley and Sons
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English
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Mutant rats (TM rats) with abnormal hepatic excretory function were used to study biliary traneport of dieromoeulfophthalein, ouabain, tributylmethyl ammonium, cholate and taurocholate. In whole animals, dib r o d o p h t h a l e i n and ouabain clearance is reduced to 7 and 37% of normal, respectiv