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Hereditary chronic conjugated hyperbilirubinemia in mutant rats caused by defective hepatic anion transport

โœ Scribed by Peter L. M. Jansen; Wilbert H. Peters; Wouter H. Lamers


Book ID
102850615
Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
762 KB
Volume
5
Category
Article
ISSN
0270-9139

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Selective hepatobiliary transport defect
โœ Peter L. M. Jansen; Geny M. M. Groothuis; Wilbert H. M. Peters; Dirk F. M. Meije ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 571 KB

Mutant rats (TM rats) with abnormal hepatic excretory function were used to study biliary traneport of dieromoeulfophthalein, ouabain, tributylmethyl ammonium, cholate and taurocholate. In whole animals, dib r o d o p h t h a l e i n and ouabain clearance is reduced to 7 and 37% of normal, respectiv