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Organic anion transport study in mutant rats with autosomal recessive conjugated hyperbilirubinemia

โœ Scribed by Hiroko Kurisu; Kazuaki Kamisaka; Toshiya Koyo; Shinobu Yamasuge; Hiroe Igarashi; Hidenori Maezawa; Takashi Uesugi; Osamu Tagaya

Book ID
118344893
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
433 KB
Volume
49
Category
Article
ISSN
0024-3205

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๐Ÿ“œ SIMILAR VOLUMES

Selective hepatobiliary transport defect
Selective hepatobiliary transport defect for organic anions and neutral steroids in mutant rats with hereditary-conjugated hyperbilirubinemia
โœ Peter L. M. Jansen; Geny M. M. Groothuis; Wilbert H. M. Peters; Dirk F. M. Meije ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 571 KB

Mutant rats (TM rats) with abnormal hepatic excretory function were used to study biliary traneport of dieromoeulfophthalein, ouabain, tributylmethyl ammonium, cholate and taurocholate. In whole animals, dib r o d o p h t h a l e i n and ouabain clearance is reduced to 7 and 37% of normal, respectiv