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Hereditary defect of hepatobiliary cysteinyl leukotriene elimination in mutant rats with defective hepatic anion excretion

โœ Scribed by Michael Huber; Albrecht Guhlmann; Peter L. M. Jansen; Dietrich Keppler


Book ID
102848352
Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
562 KB
Volume
7
Category
Article
ISSN
0270-9139

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Selective hepatobiliary transport defect
โœ Peter L. M. Jansen; Geny M. M. Groothuis; Wilbert H. M. Peters; Dirk F. M. Meije ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 571 KB

Mutant rats (TM rats) with abnormal hepatic excretory function were used to study biliary traneport of dieromoeulfophthalein, ouabain, tributylmethyl ammonium, cholate and taurocholate. In whole animals, dib r o d o p h t h a l e i n and ouabain clearance is reduced to 7 and 37% of normal, respectiv