HER-2/neupeptide specificity in the recognition of HLA-A2 by natural killer cells
โ Scribed by Larry D. Anderson Jr.; J. Michael Hudson; Cherylyn A. Savary; Bryan Fisk; David M. Gershenson; Constantin G. Ioannides
- Book ID
- 105968413
- Publisher
- Springer-Verlag
- Year
- 1999
- Tongue
- English
- Weight
- 222 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0340-7004
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๐ SIMILAR VOLUMES
A comprehensive analysis of human alloimmune cytotoxic T lymphocytes (CTLs) specific for the HLA-A2 antigen identified 11% of HLA-A2 positive cells as outliers. In total, 11 unrelated serologically indistinguishable, but distinguishable by cell-mediated lympholysis (CML) HLA-A2 positive outlier cell
Human alloimmune cytotoxic T cells, sensitized selectively against the HLA-A2 antigen, were tested on a panel of selected target cells. Five HLA-A2 positive outlier cells could be identified. These outlier cells were only weakly lysed by HLA-A2 specific CTLs, although they were serologically indisti