𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hepatobiliary transport of YM466, a novel factor Xa inhibitor, in rats

✍ Scribed by Yuji Mano; Takashi Usui; Hidetaka Kamimura


Publisher
Springer-Verlag
Year
2006
Tongue
English
Weight
731 KB
Volume
31
Category
Article
ISSN
0378-7966

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Antithrombotic effects of YM466, a synth
✍ Yoshiyuki Iwatsuki; Seiji Kaku; Yumiko Moritani; Yuta Taniuchi; Fukushi Hirayama πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 88 KB

## Abstract The antithrombotic effects of YM466, a synthetic direct inhibitor of human factor Xa (FXa), were evaluated in an arterio‐venous shunt thrombosis model in squirrel monkeys. YM466 significantly inhibited thrombus formation after continuous IV zx infusion at doses of 3–30 Β΅g/kg/h. Although

Efficient syntheses of isotopically labe
✍ Yinsheng Zhang πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 French βš– 140 KB

## Abstract PD0198961 was investigated as a potent and selective inhibitor of coagulation factor Xa for the treatment of thrombotic disorders. Radioactive and stable isotope‐labeled PD0198961 were synthesized for absorption, distribution, metabolism and elimination studies of the compound in animal