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Hepatitis C genotype 1 virus with low viral load and rapid virologic response to peginterferon/ribavirin obviates a protease inhibitor

✍ Scribed by Pearlman, Brian L.; Ehleben, Carole


Book ID
120595083
Publisher
John Wiley and Sons
Year
2013
Tongue
English
Weight
1013 KB
Volume
59
Category
Article
ISSN
0270-9139

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## Abstract Patients with high viral load (β‰₯1.0 × 10^5^ IU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve high sustained virological response rates to interferon (IFN)/ribavirin combination therapy. Previous studies suggested that pretreatment amino acid (aa) substitution patterns in the