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Baseline factors and early viral response (week 4) to antiviral therapy with peginterferon and ribavirin for predicting sustained virologic response in patients infected with hepatitis C virus genotype 1: A multicenter study

โœ Scribed by Toyoda, Hidenori; Kumada, Takashi; Shimada, Noritomo; Takaguchi, Koichi; Ide, Tatsuya; Sata, Michio; Ginba, Hiroyuki; Matsuyama, Kazuhiro; Izumi, Namiki


Book ID
118763091
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
98 KB
Volume
85
Category
Article
ISSN
0146-6615

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## Abstract Patients with high viral load (โ‰ฅ1.0โ€‰ร—โ€‰10^5^ IU/ml) of hepatitis C virus (HCV) genotype 1b do not achieve high sustained virological response rates to interferon (IFN)/ribavirin combination therapy. Previous studies suggested that pretreatment amino acid (aa) substitution patterns in the