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HEPATIC δ-AMINOLÆVULINIC ACID SYNTHETASE ACTIVITY IN PORPHYRIA CUTANEA TARDA

✍ Scribed by Moore, M.R.; Turnbull, A.L.; Barnardo, D.; Beattie, A.D.; Magnus, I.A.; Goldberg, A.


Book ID
123196171
Publisher
The Lancet
Year
1972
Tongue
English
Weight
480 KB
Volume
300
Category
Article
ISSN
0140-6736

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Hepatic uroporphyrinogen decarboxylase a
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Porphyria cutanea tarda (PCT) is caused by a decreased activity of the hepatic enzyme uroporphyrinogen decarboxylase (URO-D). This deficiency causes overproduction, hepatic deposition, and increased excretion of uroporphyrin. Iron overload and hepatic viral infections are considered aggravating fact