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HEPATIC DELTA-AMINOLÆVULINIC-ACID-SYNTHETASE ACTIVITY IN PORPHYRIA CUTANEA TARDA

✍ Scribed by Shanley, B.C; Joubert, S.M; Taljaard, J.J.F; Deppe, W.M


Book ID
122675410
Publisher
The Lancet
Year
1972
Tongue
English
Weight
322 KB
Volume
300
Category
Article
ISSN
0140-6736

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Porphyria cutanea tarda (PCT) is caused by a decreased activity of the hepatic enzyme uroporphyrinogen decarboxylase (URO-D). This deficiency causes overproduction, hepatic deposition, and increased excretion of uroporphyrin. Iron overload and hepatic viral infections are considered aggravating fact