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Hepatic Tumor Growth: Target for Angiogenesis Inhibition?

✍ Scribed by Shiva Sarraf-Yazdi; Jing Mi; Bryan M. Clary

Book ID
105978857
Publisher
Springer
Year
2005
Tongue
English
Weight
90 KB
Volume
29
Category
Article
ISSN
0364-2313

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## Abstract Nitroxyl (HNO) can inhibit the glycolytic enzyme glyceraldehyde 3‐phosphate dehydrogenase (GAPDH). Because of the importance of glycolysis in many malignant cells, we thus propose that HNO can adversely affect tumor growth. This hypothesis was tested using __in vitro__ and __in vivo__ m

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