The Ape-1/Ref-1 redox antagonist E3330 i
✍
Gang-Ming Zou; Collins Karikari; Yasuaki Kabe; Hiroshi Handa; Robert A. Anders;
📂
Article
📅
2009
🏛
John Wiley and Sons
🌐
English
⚖ 314 KB
## Abstract The apurinic/apyrimidinic endonuclease 1/redox factor‐1 (Ape‐1/Ref‐1) is a multi‐functional protein, involved in DNA repair and the activation of redox‐sensitive transcription factors. The Ape‐1/Ref‐1 redox domain acts as a cytoprotective element in normal endothelial cells, mitigating