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Hepatic stem cells and transforming growth factor β in hepatocellular carcinoma

✍ Scribed by Majumdar, Avijit; Curley, Steven A.; Wu, Xifeng; Brown, Powel; Hwang, Jessica P.; Shetty, Kirti; Yao, Zhi-Xing; He, Aiwu Ruth; Li, Shulin; Katz, Lior; Farci, Patrizia; Mishra, Lopa


Book ID
119995901
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
793 KB
Volume
9
Category
Article
ISSN
1759-5045

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Cancer stem cells (CSCs) are critical for the initiation, propagation, and treatment resistance of multiple cancers. Yet functional interactions between specific signaling pathways in solid organ "cancer stem cells," such as those of the liver, remain elusive. We report that in regenerating human li