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Transforming growth factor-β induces contraction of activated hepatic stellate cells

✍ Scribed by Kusum K. Kharbanda; David D. Rogers II; Todd A. Wyatt; Michael F. Sorrell; Dean J. Tuma


Book ID
116650324
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
250 KB
Volume
41
Category
Article
ISSN
0168-8278

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Transforming growth factor β and tumor n
✍ Bernhard Saile; Nina Matthes; Thomas Knittel; Giuliano Ramadori 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 244 KB

Transforming growth factor ␤ (TGF-␤) as well as tumor necrosis factor ␣ (TNF-␣) gene expression are up-regulated in chronically inflamed liver. These cytokines were investigated for their influence on apoptosis and proliferation of activated hepatic stellate cells (HSCs). Spontaneous apoptosis in ac