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Down-regulation of endothelin receptors by transforming growth factor β1 in hepatic stellate cells

✍ Scribed by Adelheid Gabriel; Ruhul H Kuddus; Abdul S Rao; Chandrashekhar R Gandhi

Book ID
118568968
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
1015 KB
Volume
30
Category
Article
ISSN
0168-8278

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## Abstract Previous studies have demonstrated that transforming growth factor‐β3 (TGF‐β3) protected liver against fibrosis in vivo and vitro, but its regulation is poorly understood. In addition, the cAMP‐responsive element (CRE) in TGF‐β3 promoter is recognized as an important regulatory site for