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Hepatic regeneration in insulin-like growth factor binding protein-1 transgenic mice

✍ Scribed by Yong-Yu Liu; Kadaba Rajkumar; Liam J Murphy


Book ID
118569033
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
820 KB
Volume
30
Category
Article
ISSN
0168-8278

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## Abstract Insulin‐like growth factor binding protein‐1 (IGFBP‐1) is synthesized in the liver and regulates the mitogenic effects of the insulin‐like growth factors (IGFs). The evidence that IGFBP‐1 plays a role in hepatocarcinogenesis, however, is equivocal. We have, therefore, investigated the d