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Hepatic iron metabolism gene expression profiles in HFE associated Hereditary Hemochromatosis

✍ Scribed by Ferga Gleeson; Eleanor Ryan; Sharon Barrett; Jennifer Russell; John Crowe

Book ID
116304194
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
430 KB
Volume
38
Category
Article
ISSN
1079-9796

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Homozygosity for the mutation Cys282Tyr in the HFE gene has recently been identified as a cause of hereditary hemochromatosis, a disorder resulting in the inappropriate absorption of iron. Approximately 10% of Caucasians are heterozygous for this mutation; however, the gene frequency in African Amer