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Heparin-Binding EGF-like Growth Factor Is an Autocrine Growth Factor for Rat Gastric Epithelial Cells

✍ Scribed by Yoshiji Miyazaki; Yasuhisa Shinomura; Shigeki Higashiyama; Shuji Kanayama; Yoshifumi Higashimoto; Shusaku Tsutsui; Shinichiro Zushi; Naoyuki Taniguchi; Yuji Matsuzawa


Book ID
115578544
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
455 KB
Volume
223
Category
Article
ISSN
0006-291X

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Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) is a member of the EGF family and is highly expressed in hepatoma tissues but not in normal liver. However, it is unknown when HB-EGF is induced during hepatocarcinogenesis and what are the mechanisms underlying its high expre