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Heparin-Binding EGF-like Growth-Factor Is a Potent Mitogen for Rat Hepatocytes

โœ Scribed by N. Ito; S. Kawata; S. Tamura; S. Kiso; H. Tsushima; D. Damm; J.A. Abraham; S. Higashiyama; N. Taniguchi; Y. Matsuzawa


Book ID
115574039
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
352 KB
Volume
198
Category
Article
ISSN
0006-291X

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Heparin-binding epidermal growth factor (EGF)-like growth factor (HB-EGF) is a member of the EGF family and is highly expressed in hepatoma tissues but not in normal liver. However, it is unknown when HB-EGF is induced during hepatocarcinogenesis and what are the mechanisms underlying its high expre