𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hemolysin production in spleen and peripheral blood cells from normal and leukemic chicks. I. Quantitative assay

✍ Scribed by Bengt Lagerlöf; Pär Sundelin

Publisher
John Wiley and Sons
Year
1970
Tongue
French
Weight
384 KB
Volume
5
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Cell suspensions from spleen, peripheral blood, thymus and bursa of Fabricius of normal chicks and cells from spleen and peripheral blood of chicks with myeloid leukemia were investigated by the hemolytic plaque technique. Spleen cells from normal chicks older than 14 days produced maximum relative numbers of hemolytic foci 5 days after immunization. No signs of hemolysin production were found in cells from peripheral blood, thymus or bursa of Fabricius from non‐leukemic chicks.

Spleen cell suspensions from many chicks with myeloid leukemia produced fewer hemolytic foci than spleen cells from normal chicks. However, in some leukemic chicks the immunological reactivity per spleen was similar to that of non‐leukemic spleens. In these chicks white cells in peripheral blood were also capable of PFU formation.

📜 SIMILAR VOLUMES

Hemolysin production in spleen and perip
Hemolysin production in spleen and peripheral blood cells from normal and leukemic chicks. II. Ultrastructural analysis of the plaque-forming cells
✍ Bengt Lagerlöf; Par Sundelin 📂 Article 📅 1970 🏛 John Wiley and Sons 🌐 French ⚖ 383 KB 👁 1 views

## Abstract The cells of normal and leukemic chicks producing hemolytic plaques in agar after stimulation with SRBC have been examined ultrastructurally. The plaque‐forming cells from non‐leukemic chicks were generally plasma cells. This was also the case for 21 of 30 plaques formed by spleen or pe

The in vitro production of antibodies to
The in vitro production of antibodies to mitochondrial antigens by peripheral blood mononuclear cells from patients with primary biliary cirrhosis
✍ Mark I. Avigan; Gregory Adamson; Jay H. Hoofnagle; E. Anthony Jones 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 684 KB

Primary biliary cirrhosis (PBC) is a disease that typically affects middle-aged women and is characterized by progressive intrahepatic cholestasis which leads ultimately to cirrhosis, portal hypertension and hepatocellular failure (1). The underlying histopathological lesion in PBC is a chronic, non