Heme oxygenase (HO) catalyzes the oxidative cleavage of the β£-mesocarbon of Fe-protoporphyrin-IX yielding equimolar amounts of biliverdin-IXa, iron, and carbon monoxide. The HO-system consists of two isoenzymes, namely HO-2 and the inducible isoform HO-1, also referred to as heat shock protein (hsp)
Heme oxygenase 1 expression in rat liver during ageing and ethanol intoxication
β Scribed by Stefania Patriarca; Anna Lisa Furfaro; Luana Cosso; Elena Pesce Maineri; Emanuela Balbis; Cinzia Domenicotti; Mariapaola Nitti; Damiano Cottalasso; Umberto Maria Marinari; Maria Adelaide Pronzato; Nicola Traverso
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 176 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1389-5729
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Heme oxygenase (HO) catalyzes the conversion of heme into biliverdin, iron, and carbon monoxide (CO). Two isoforms of HO have been identified: the inducible HO-1 and the constitutive HO-2. CO, like nitric oxide, is an endogenous vasodilator that could contribute to modulation of systemic and local v
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