Tetramethylpyrazine induces heme oxygenase-1 expression and attenuates myocardial ischemia/reperfusion injury in rats
โ Scribed by Shu-Ying Chen; George Hsiao; Hwong-Ru Hwang; Pao-Yun Cheng; Yen-Mei Lee
- Publisher
- BioMed Central
- Year
- 2006
- Tongue
- English
- Weight
- 279 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1021-7770
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๐ SIMILAR VOLUMES
We investigated whether native macrophages overexpressing heme oxygenase 1 (HO-1) could protect rat orthotopic liver transplant (OLT) against cold ischemia/reperfusion injury (IRI). Livers from Sprague-Dawley rats were stored at 4 C in University of Wisconsin solution for 24 hours, and then they wer
Heme oxygenase (HO) isozymes, HO-1 and HO-2 catalyze the cleavage of heme b to form the antioxidant biliverdin IXa, iron and the putative cellular messenger carbon monoxide (CO). Heat and stress have been reported to induce the expression of HO-1, in analogy to ubiquitin, a protein of 8 kDa involved