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Hematopoietic stem cell gene therapy for adenosine deaminase deficient-SCID

✍ Scribed by Alessandro Aiuti; Immacolata Brigida; Francesca Ferrua; Barbara Cappelli; Robert Chiesa; Sarah Marktel; Maria-Grazia Roncarolo


Book ID
107572438
Publisher
Springer-Verlag
Year
2009
Tongue
English
Weight
241 KB
Volume
44
Category
Article
ISSN
0257-277X

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PEG-ADA: An alternative to haploidentica
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PEG-ADA is a long-circulating form of adenosine deaminase (ADA) that has been in use for > 8 years as replacement therapy for severe combined immunodeficiency disease due to ADA deficiency. Treatment with PEG-ADA almost completely corrects metabolic abnormalities, allowing the recovery of a variable