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Selective Expansion of Transduced Cells for Hematopoietic Stem Cell Gene Therapy

✍ Scribed by Akihiro Kume; Yutaka Hanazono; Hiroaki Mizukami; Takashi Okada; Keiya Ozawaa

Publisher
Carden Jennings Publishing
Year
2002
Tongue
English
Weight
236 KB
Volume
76
Category
Article
ISSN
0925-5710

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## Abstract ## Background Hematopoietic stem‐cell‐directed gene transfer has achieved limited success in transducing clinically relevant levels of target cells. The expansion of gene‐modified cells is one way to circumvent the problem of inefficient transduction with current vectors. To this end,