Hematopoietic Stem Cell Development

✍ Scribed by Isabelle Godin Ph.D, Ana Cumano M.D. (auth.)

• Publisher: Springer US
• Year: 2006
• Tongue: English
• Leaves: 187
• Series: Medical Intelligence Unit
• Edition: 1
• Category: Library

✦ Synopsis

Hematopoietic Stem Cells brings together articles covering the biology of hematopoietic stem cells during embryonic development, reporting particular aspects of fly, fish, avian and mammalian models. Thus, this book allows a comparative overview of hematopoietic stem cell generation in the different classes, emphasizing the conserved trends in development. This book culminates with state-of –the art knowledge on hematopoietic development in human species and discussions of the most recent breakthroughs with relevance to both researchers and clinicians.

✦ Table of Contents

Front Matter....Pages i-xii
Ventral and Dorsal Contributions to Hematopoiesis in Xenopus ....Pages 1-13
Genetic Dissection of Hematopoiesis Using the Zebrafish....Pages 14-31
Extra- and Intraembryonic HSC Commitment in the Avian Model....Pages 32-45
Avian Lymphopoiesis and Transcriptional Control of Hematopoietic Stem Cell Differentiation....Pages 47-61
Yolk Sac Development in Mice....Pages 62-71
Long-Term Reconstituting Hematopoietic Stem Cell Capacity in the Embryo....Pages 72-79
The Endothelium: The Cradle of Definitive Hematopoiesis?....Pages 80-91
Endothelial and Hematopoietic Cells in the Intraembryonic Compartment....Pages 92-107
Origin and Fate of Hematopoietic Precursors in the Early Mouse Embryo....Pages 108-123
Hematopoietic Development in Drosophila : A Parallel with Vertebrates....Pages 124-141
Intraembryonic Development of Hematopoietic Stem Cells during Human Ontogeny: Expression Analysis....Pages 142-153
Gene and Cell Therapy Involving Hematopoietic Stem Cell....Pages 154-173
Back Matter....Pages 175-178

✦ Subjects

Biomedicine general; Human Genetics; Cell Biology; Developmental Biology