Surface salt bridges stabilize the GCN4
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Erik J. Spek; Au H. Bui; Min Lu; Neville R. Kallenbach
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Article
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1998
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Cold Spring Harbor Laboratory Press
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English
β 671 KB
## Abstract We present a study of the role of salt bridges in stabilizing a simplified tertiary structural motif, the coiledβcoil. Changes in GCN4 sequence have been engineered that introduce trial patterns of single and multiple salt bridges at solvent exposed sites. At the same sites, a set of al