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Dissociation and unfolding of GCN4 leucine zipper in the presence of sodium dodecyl sulfate

✍ Scribed by Fan-Guo Meng; Xiangang Zeng; Yuan-Kai Hong; Hai-Meng Zhou


Book ID
117456680
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
84 KB
Volume
83
Category
Article
ISSN
0300-9084

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The relationship between the unfolding pseudo free energies of reduced and detailed atomic models of the GCN4 leucine zipper is examined. Starting from the native crystal structure, a large number of conformations ranging from folded to unfolded were generated by all-atom molecular dynamics unfoldin