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Hearing the messenger: Ins(1,4,5)P3 and deafness

โœ Scribed by Bruzzone, Roberto; Cohen-Salmon, Martine


Book ID
109911249
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
315 KB
Volume
7
Category
Article
ISSN
1465-7392

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Role of PRIP-1, a novel Ins(1,4,5)P3 bin
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## Abstract PRIPโ€1 was isolated as a novel inositol 1,4,5โ€trisphosphate [Ins(1,4,5)P~3~] binding protein with a domain organization similar to phospholipase Cโ€ฮด1 (PLCโ€ฮด1) but lacking the enzymatic activity. Further studies revealed that the pleckstrin homology (PH) domain of PRIPโ€1 is the region re