Transgenic mice have been created that carry human immunoglobulin heavy and light chain genes in germline configuration and that have the corresponding endogenous genes silenced. The transgenes are either minigene constructs or large, almost authentic, transloci on yeast artificial chromosomes and u
HBV production in transgenic mice
β Scribed by Yamamura, Ken-ichi ;Araki, Kimi ;Hino, Okio ;Tomita, Naohiro ;Miyazaki, Jun-ichi ;Matsubara, Kenichi
- Publisher
- Springer-Verlag
- Year
- 1990
- Tongue
- English
- Weight
- 323 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0435-1339
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