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Haplotype analysis of the apolipoprotein gene cluster on human chromosome 11

โœ Scribed by Michael Olivier; Xujing Wang; Regina Cole; Brian Gau; Jessica Kim; Edward M Rubin; Len A Pennacchio


Book ID
116981219
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
510 KB
Volume
83
Category
Article
ISSN
0888-7543

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The Advantages of Haplotype Analysis of
โœ Daniel Peter McLaughlin; Anita Sharma; Ann McGinley; Gurdip Singh Samra ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 810 KB

Polymorphisms in the regulatory region of the human apolipoprotein E gene (gene, APOE; protein, apoE) have been implicated in Alzheimer's disease. Here we describe in detail the advantages of a simple method for haplotype analysis of this region (at -491 and -427 bases relative to the transcription