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DNA polymorphism haplotypes of the human apolipoprotein APOA1-APOC3-APOA4 gene cluster

โœ Scribed by Stylianos E. Antonarakis; Peter Oettgen; Aravinda Chakravarti; Susan L. Halloran; Richard R. Hudson; Lila Feisee; Sotirios K. Karathanasis

Publisher
Springer
Year
1988
Tongue
English
Weight
1006 KB
Volume
80
Category
Article
ISSN
0340-6717

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Lipoprotein lipase (LPL) plays a central role in the metabolism of lipoproteins by hydrolyzing the core triglycerides of circulating very low density lipoproteins and chylomicrons. The enzyme is encoded by a gene about 30kb in size located on the short arm of human chromosome 8. We have determined t