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Haplotype block structure of the cytochrome P450 CYP2C gene cluster on chromosome 10

✍ Scribed by Walton, Robert; Kimber, Martin; Rockett, Kirk; Trafford, Clare; Kwiatkowski, Dominic; Sirugo, Giorgio


Book ID
109916811
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
232 KB
Volume
37
Category
Article
ISSN
1061-4036

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We have studied the genetic linkage of two markers, the apolipoprotein C1 (APOC1) gene and a cytochrome P450 (CYP2A) gene, in relation to the gene for myotonic dystrophy (DM). A peak lod score of 9.29 at 2 cM was observed for APOC1-DM, with a lod score of 8.55 at 4 cM for CYP2A-DM. These two markers