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Haploidentical Stem Cell Transplantation: An Emerging Treatment Modality

✍ Scribed by Taner Demirer (eds.)

Publisher
Humana Press
Year
2017
Tongue
English
Leaves
205
Series
Stem Cell Biology and Regenerative Medicine
Edition
1
Category
Library
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✦ Synopsis

This book discusses the aspects of haploidentical transplants and will shed light on the debates and questions on this burgeoning field and timely topic. Donor selection, graft failure, minimal CD34+ cell requirement, and conditioning regimens used for haploidentical transplants will be written by expert authors dealing with this type of transplants. Approximately one third of the books' chapters cover logic and basic aspects; the remaining two thirds of the book discuss clinical aspects, outcomes, and future perspectives, thus providing a comphrensive discussion of the topic. Haploidentical transplantation is extremely timely, rapidly-changing area and increasing its use will decrease the need for time-consuming, expensive, unrelated donor search. Moreover, Haploidentical Stem Cell Transplantation brings a set of clear answers to questions of feasibility, advantages over unrelated transplants, cost effectivity and outcome..

✦ Table of Contents

Front Matter ....Pages i-xv
General Indications and Logic for Haploidentical SCT (Florent Malard, Mohamad Mohty)....Pages 1-7
Donor Selection and Cell Dose in Haploidentical SCT (Riad El Fakih, Mutlu Arat, Mahmoud Aljurf)....Pages 9-16
Graft Failure and Rejection in Haploidentical Stem Cell Transplantation (Miguel Blanquer, Jose M. Moraleda)....Pages 17-41
Toxicity of Conditioning Regimens in Haploidentical SCT (Meltem Kurt YΓΌksel, Taner Demirer)....Pages 43-56
An Overview of the Prophylaxis and Treatment of GvHD in Haploidentical SCT (Fabio Ciceri)....Pages 57-65
Prevention and Treatment of Infectious Complications in Haploidentical SCT (Angela Haßler, Thomas Lehrnbecher, Peter Bader, Thomas Klingebiel)....Pages 67-93
Graft Versus Leukemia (GvL), Graft Versus Lymphoma Effect in Haploidentic SCT (Jakob R. Passweg, Michael Medinger, Joerg P. Halter)....Pages 95-102
Outcome of Haploidentical SCT in Patients with Acute Leukemia (Albert Esquirol, Jorge Sierra)....Pages 103-117
Outcome of Haploidentical Stem Cell Transplantation in Patients with Lymphoma (RocΓ­o Parody, Anna Sureda)....Pages 119-140
Applications of Haploidentical SCT in Patients with Non-malignant Diseases (Nicolaus KrΓΆger)....Pages 141-147
Applications of Haploidentical SCT in Pediatric Patients (Marco Zecca, Patrizia Comoli)....Pages 149-178
Innovative Approaches to Increase the Success of the Haploidentical SCT (Ulas D. Bayraktar, Stefan O. Ciurea)....Pages 179-187
Future Perspectives for Haploidentical SCT (Ugur Sahin, Taner Demirer)....Pages 189-199

✦ Subjects

Stem Cells

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