𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Halo lipids, 8. Synthesis of O-alkyl-O-alkyl-O-(2,2,2-trifluoroethyl)glycerols and O-alkyl-O-(2,2,2-trifluoroethyl)glycero-phosphocholines

✍ Scribed by H. Brachwitz; P. Franke; R. Hintsche; P. Langen; J. Schildt


Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
805 KB
Volume
36
Category
Article
ISSN
0009-3084

No coin nor oath required. For personal study only.

✦ Synopsis


The syntheses and structure determination of 3 positional isomers of O-alkyl-O-(2,2,2-trilluoroethyl)glycerols and their conversion into the corresponding O-alkyl-O-(2,2,2-tritluoroethyl)glycerophosphocholines via the [O-alkyl-O-(2,2,2-trifluoroethyl)~ycero]-2-bromoethyl hydrogen phosphates are described.


📜 SIMILAR VOLUMES


Synthesis of [32P]labelled 1-O-alkyl-2-d
✍ H. P. Deigner; B. Fyrnys 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 French ⚖ 195 KB

## Abstract The syntheses of N‐substituted 1‐O‐alkyl‐2‐desoxy‐2‐amino‐__sn__‐glycero‐3‐[^32^P]phosphocholines were performed in four steps starting from [^32^P] POCl~3~ and the corresponding 1‐O‐alkyl‐2‐amino‐propane‐3‐ols in 5‐7% total yield.

Synthesis and fungicidal activity of O-a
✍ Liang Han; Jian-Rong Gao; Zheng-Ming Li 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 126 KB 👁 1 views

## Abstract __N__‐stearoylethanolamine (NAE18:0) was reacted with O‐alkyl O‐aryl chlorophosphate and a series of O‐alkyl O‐aryl O‐2‐(stearamido)ethyl phosphates were synthesized to explore their antifungal activity. Compared with parent NAE18:0, title compounds without substitution or with methyl s

Synthesis and proaggregatory activity of
✍ B. Schmid; G. Ostermann; H.-P. Kertscher 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 344 KB

Racemic l-O-(2-methyloctadecyl)-2-O-acetyl-glycero-3-phosphocholine, a branched chain PAF species, was prepared by chemical synthesis and investigated for biological activity on human blood platelets in vitro. The synthesis started from 2-O-benzylglycerol and 2-methyloctadecyl-l-methyl sulfonate and

A facile method for the preparation of 1
✍ Toshio Muramatsu; Nagao Totani; Helmut K. Mangold 📂 Article 📅 1981 🏛 Elsevier Science 🌐 English ⚖ 343 KB

Biologically active l-O-alkyl-2-O-acetoyl-sn-glycero-3-phosphocholines are prepared in good yields from raffish (Hydrolagus colliei) liver oil, an inexpensive natural product, that contains over 70% neutral ether lipids.

Synthesis of 1,3-di-O-alkyl-2-O-(β-glyco
✍ Hiroyuki Minamikawa; Teiichi Murakami; Masakatsu Hato 📂 Article 📅 1994 🏛 Elsevier Science 🌐 English ⚖ 534 KB

A novel series of synthetic glycolipids, i,3-di-O-alkyl-2-O-(/3-glycosyl)glycerols, and their efficient synthetic route were proposed. These glyceroglycolipids were synthesized in good overall yields and stereoselectivity in five steps via trichloroacetimidate glycosylation with 1,3-di-O-alkylglycer