Hallucinations and ifosfamide-induced neurotoxicity
β Scribed by Joseph R. Dimaggio; Walter F. Baile; Rayna Brown; David Schapira
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 612 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0008-543X
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We read with interest the article on ifosfamide-induced hyperpigmentation by Teresi et al.' In our experience, this is a widespread, if underreported phenomenon. In Newcastle, United Kingdom, children with nonmetastatic soft tissue sarcomas are initially treated with five courses of ifosfamide (IF)
## Abstract We describe 2 cases of proximal tubular defects induced by the administration of ifosfamide at a dosage of 6 g/m^2^/course over 2 days in children with a diagnosis of malignant mesenchymal tumors. This adverse effect could be minimized dividing dosage of the drug. However at present it