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Ifosfamide-induced renal tubular defect

✍ Scribed by Valdivieso, María José Torres ;Pérez, Jesús López ;Melero, Carmen ;Vivanco, José Luis ;Muley, Rafael ;Vara, Julia

Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
317 KB
Volume
22
Category
Article
ISSN
0098-1532

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✦ Synopsis

Abstract

We describe 2 cases of proximal tubular defects induced by the administration of ifosfamide at a dosage of 6 g/m^2^/course over 2 days in children with a diagnosis of malignant mesenchymal tumors. This adverse effect could be minimized dividing dosage of the drug. However at present it is not clear if divided doses are completely safe.

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