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Hallmarks of protein oxidative damage in neurodegenerative diseases: focus on Alzheimer’s disease

✍ Scribed by M. C. Polidori; H. R. Griffiths; E. Mariani; P. Mecocci

Publisher
Springer
Year
2007
Tongue
English
Weight
185 KB
Volume
32
Category
Article
ISSN
0939-4451

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## Abstract Increasing evidence supports a role for oxidative damage in the pathogenesis of Alzheimer's disease (AD). Multiple studies show significantly increased levels of lipid peroxidation and protein, DNA, and RNA oxidation in vulnerable regions of the brain of patients with late‐stage AD (LAD