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Guanine nucleotide regulation of agonist interactions at [3H]SCH23390-labeled D1 dopamine receptors in rat striatum

✍ Scribed by Ellen J. Hess; George Battaglia; Andrew B. Norman; Louis C. Iorio; Ian Creese

Book ID: 115880043
Publisher: Elsevier Science
Year: 1986
Tongue: English
Weight: 574 KB
Volume: 121
Category: Article
ISSN: 0014-2999
DOI: 10.1016/0014-2999(86)90389-4

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A novel benzazepine, SCH 23390, has recently been described as a very potent and selective dopamine D-1 receptor antagonist based on its potent inhibition of dopamine sensitive adenylate cyclase and its selective displacement of 3H-piflutixol from rat striatal receptor sites. In the present study, t