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Characterization of the binding of 3H-SCH 23390, a selective D-1 receptor antagonist ligand, in rat striatum

✍ Scribed by William Billard; Vilma Ruperto; Gordon Crosby; Louis C. Iorio; Allen Barnett


Book ID
118340659
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
398 KB
Volume
35
Category
Article
ISSN
0024-3205

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Characterization of the binding of 3H-SC
✍ William Billard; Vilma Ruperto; Gordon Crosby; Louis C. Iorio; Allen Barnett πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 English βš– 398 KB

A novel benzazepine, SCH 23390, has recently been described as a very potent and selective dopamine D-1 receptor antagonist based on its potent inhibition of dopamine sensitive adenylate cyclase and its selective displacement of 3H-piflutixol from rat striatal receptor sites. In the present study, t