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Growth inhibitory effect of p21 and p53 containing adenoviruses on transitional cell carcinoma cell lines in vitro and in vivo

✍ Scribed by Terence W McGarvey; Raymond D Meng; Omari Johnson; Wafik El-Deiry; S.Bruce Malkowicz


Book ID
117724125
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
360 KB
Volume
6
Category
Article
ISSN
1078-1439

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## Abstract ## Background. Although cyclooxygenase‐2 (COX‐2) has been suggested to play an important role in carcinogenesis, the effects of tumor suppressors on COX‐2 gene expression and the combined antitumor effects of tumor suppressors and COX‐2 inhibitors have rarely been investigated. ## Met