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Effects of Selaginella tamariscina on in vitro tumor cell growth, p53 expression, G1 arrest and in vivo gastric cell proliferation

✍ Scribed by In-Seon Lee; Akiyoshi Nishikawa; Fumio Furukawa; Ken-ichiro Kasahara; Soo-Un Kim


Book ID
117469562
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
346 KB
Volume
144
Category
Article
ISSN
0304-3835

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Chalcone HTMC causes in vitro selective
✍ Yerra Koteswara Rao; Te-Yu Kao; Jiunn-Liang Ko; Yew-Min Tzeng πŸ“‚ Article πŸ“… 2010 πŸ› Elsevier Science 🌐 English βš– 680 KB

The present Letter identified 2 0 -hydroxy-2,3,4 0 ,6 0 -tetramethoxychalcone (HTMC) as a potent in vitro cytotoxic agent with selective activity against cell lines derived from human lung cancer. In A549 lung adenocarcinoma cells, HTMC caused G1 phase cell-cycle arrest. HTMC treatment also led to a