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Growth inhibitory effect of eicosapentaenoic acid on cultured human epidermal keratinocytes

✍ Scribed by Riku, Rou; Nakatani, Shuzo; Okada, Natsuko; Yoshikawa, Kunihiko


Book ID
122495674
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
423 KB
Volume
5
Category
Article
ISSN
0923-1811

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The role and mechanisms of action of insulin-like growth factors (IGFs) in skin remain unclear. Epidermal keratinocytes possess IGF-I receptors and are responsive to IGF-I, which is primarily derived from underlying dermal fibroblasts. IGF binding proteins (IGFBPs), also synthesized by fibroblasts,