The role and mechanisms of action of insulin-like growth factors (IGFs) in skin remain unclear. Epidermal keratinocytes possess IGF-I receptors and are responsive to IGF-I, which is primarily derived from underlying dermal fibroblasts. IGF binding proteins (IGFBPs), also synthesized by fibroblasts,
β¦ LIBER β¦
Epidermal growth factor and the multiplication of cultured human epidermal keratinocytes
β Scribed by Rheinwald, James G.; Green, Howard
- Book ID
- 109703726
- Publisher
- Nature Publishing Group
- Year
- 1977
- Tongue
- English
- Weight
- 483 KB
- Volume
- 265
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/265421a0
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