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Griseofulvin for eosinophilic fasciitis

✍ Scribed by Mario Giordano; Marisa Ara; Carmine Cicala; Gabriele Valentini; Ugo Chianese


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
208 KB
Volume
23
Category
Article
ISSN
0004-3591

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## Abstract Two patients with clinical and pathologic features of eosinophilic fasciitis manifested serologic and systemic abnormalities that raised the question of the fundamental nature and relationship of eosinophilic fasciitis to scleroderma. In addition to the characteristic features of eosino

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## LETTERS eration was observed only in the superficial area. According to the 73 previously reported cases, the main inflammatory lesions are located in the fascia, and muscle involvement was only observed in half of these patients. These observations suggest that the fascia is damaged primarily,

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Capillary microscopy was performed on 19 patients with eoslnophilic fasciitis. These patients were compared with 13 individuals with progressive systemic sclerosis (scleroderma). Capillary patterns were normal in 16 of 19 (84%) eosinophilic fasciitis patients; 3 exhibited either borderline or nonspe

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## Abstract Serum eosinophil chemotactic activity was determined by the Boyden chamber technique in 20 patients with eosinophilic fasciitis. Increased eosinophil chemotactic activity (>125% of background) was found in all 20 patients (mean 297% Β± 129), whereas sera of 20 controls with systemic scle

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Circulating immune complexes in eosinoph
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## Abstract Serum immune complexes were measured in 22 patients with eosinophilic fasciitis, 8 of whom had serial determinations. Elevated levels were found by Raji cell radioimmunoassay in 14 (64%) patients, by agarose gel electrophoresis in 13 (59%), and by C1q agglutination‐inhibition in 9 (41%)