✦ LIBER ✦

Circulating immune complexes in eosinophilic fasciitis

✍ Scribed by James R. Seibold; Gerald P. Rodnan; Thomas A. Medsger Jr; Alan Winkelstein

Publisher: John Wiley and Sons
Year: 1982
Tongue: English
Weight: 566 KB
Volume: 25
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780251006

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Serum immune complexes were measured in 22 patients with eosinophilic fasciitis, 8 of whom had serial determinations. Elevated levels were found by Raji cell radioimmunoassay in 14 (64%) patients, by agarose gel electrophoresis in 13 (59%), and by C1q agglutination‐inhibition in 9 (41%). Elevated levels by Raji cell assay were present more frequently at times of active disease [17 of 22 sera (77%)] than at times of inactive disease [2 of 24 (8%) (P<0.0005)] and were more closely correlated with disease activity than were eosinophilia, hypergammaglobulinemia, or increased erythrocyte sedimentation rate.

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